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This characterization of all nuclei revealed that the majority of nuclei could be broadly associated with a 40° 〈1 1 1〉 misorientation to the matrix in which they formed, while a much lower percentage were found to have orientations as those of the local deformation substructure.
Using our algorithm, the number of cells counted depends on the surface area of the majority of nuclei in the image.
C. BIRC levels in LTL-418 xenograft tissue 3 weeks after castration showing high level of staining in absolute majority of nuclei.
Interestingly, the majority of nuclei were stained in FTC, whereas in PTC, and UTC, (not shown) only few nuclei were TKTL1-positive.
As previously observed in multiple normal and malignant cell types [ 9, 19], T-oligo rapidly localized to the nuclei comparably well in both cell types and the majority of nuclei were positive.
This marker showed in the majority of nuclei no difference between the doughnut- and cap-like structure and other nuclear parts, even when the H3.1/3.2 signal was decreasing (Fig. 7G,H).
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Currently, the majority of nucleus-encoded mitochondrial proteins are unknown even for model plant Arabidopsis.
Similarly, for Tsga2, the signal was detectable only in 37% of late zygotene to early pachytene cells in T+/+T43H (P = 3.1E−06; compared to B6; one-sided Fisher's exact test) and in 23% of t 12 +/+T43H samples (P = 1.37E−08), whereas the majority of the nuclei of fertile males were positive, 91% of B6 nuclei and 83% of t 12 /+ nuclei (Fig. 6b).
With DUX4+ nuclei constituting only 0.3% of the bulk population of cultured FSHD muscle cells, changes in the ratios of NMD and non-NMD isoforms in these DUX4+ nuclei are swamped by the normal levels expressed by the vast majority of DUX4− nuclei.
These findings exclude the possibility that the observed DNA synthesis can be explained by widespread cardiomyocyte polyploidization, as the latter would result in the majority of BrdU+/TnI+ nuclei being at least tetraploid (or octoploid/hexadecaploid) as well as in different ploidy distributions between BrdU+/TnI+ and BrdU−/TnI+ cardiomyocyte nuclei (with BrdU+ nuclei having higher DNA content).
In the vast majority of HMEC nuclei, a line scan throughout the XIST-positive X showed that the increase of the intensity of the XIST RNA signal had the same trend of DAPI, whereas Cot-1 RNA signal was depleted (Figure 5D).
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