Sentence examples for majority of mb from inspiring English sources

However, the majority of MB needs to be labeled with fluorescence and quenching molecules on the two ends of the probe, and observed the reaction of fluorescence or complicated electrochemical signal produced hybridization of MB and target sequence by complex and expensive instruments.

As expected, the majority of MB leprosy patients were identified by serological assays, yielding higher responses than PB patients.

The majority of MB tumors bear low MYC levels and high levels of JAG1, which triggers pro-proliferative signaling through NOTCH2.

Compared with normal human fetal cerebellum, a decreased expression level of miR-9 was observed in the majority of MB tumour tissues and in all the six MB cell lines tested.

Secondly, we have shown that although MGMT is expressed in the majority of MB patients' tumours, and is able to directly repair the effects of DNA alkylating agents it cannot repair the effects of two novel imidazotetrazine derivatives of TMZ (N-3 sulfoxide and N-3 propargyl) in MB cells.

JAG1 is highly expressed in the vast majority of MBs and homogeneously distributed across subgroups; moreover, JAG1 depletion inhibited pro-proliferative NOTCH2 signals and caused a decrease in expression of HES1, which plays a central role in MB pathogenesis [ 39- 42].

The research revealed a significant over-expression of ligand JAG1 in the vast majority of MBs, and proved that JAG1 mediates pro-proliferative signals via activation of NOTCH2 receptor and induction of HES1 expression, thus representing an attractive therapeutic target.

Not surprisingly, the majority of published MB mouse models have thus been associated with these developmental signaling pathways.

Similarly, while the majority of sorted MB and BPC lacked CK8 expression, there was a sub-population of EpCAMlo/neg/CD49f+ cells that co-expressed both CK8 and CK14 markers.

In summary, the majority of published MB GEM and related models are associated with the Shh signaling pathway using either a Ptc or a Tp53 mutant background.

For the analysis of osteoblast and osteoclast numbers per mm bone surface we focused on trabecular bone, as the majority of MDA-MB-231 tumours appear to originate in the trabeculae rich metaphysis area [11,22].