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The majority of malaria cases occur in Africa.
What of Africa, where the vast majority of malaria cases, and deaths from the disease occur?
This is likely because the majority of malaria vaccine candidates have only recently entered clinical evaluation.
Plasmodium vivax parasites cause the majority of malaria cases outside Africa, and are increasingly being acknowledged as a cause of severe disease.
The majority of malaria cases are caused by Plasmodium falciparum and Plasmodium vivax, which differ in virulence, red blood cell tropism, cytoadhesion of infected erythrocytes, and dormant liver hypnozoite stages.
"Air temperatures below approximately 18°C and 15°C (64.4°F and 59°F) stop the development of the Plasmodium falciparum and P. vivax parasites, respectively, which are responsible for the majority of malaria cases in Ethiopia," write the authors, led by Bradfield Lyon, a research professor at the University of Maine and adjunct research scientist at IRI.
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Plasmodium falciparum is the species responsible for the vast majority of malaria-related morbidity and mortality.
The human malaria parasite Plasmodium falciparum is responsible for the vast majority of malaria-related mortality.
The human malaria parasite Plasmodium falciparum is responsible for the majority of malaria-related deaths.
Resistance to virtually all classes of antimalarial drugs has evolved in natural populations of Plasmodium falciparum, the human malaria parasite species responsible for the great majority of malaria-attributed child mortality and morbidity.
P. falciparum is responsible for the majority of severe malaria and malaria-associated deaths worldwide, particularly in sub-Saharan Africa where severe malaria has a disproportionate impact on children <5 years of age (WHO, 2012).
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