Sentence examples for majority of internalized from inspiring English sources
At 15 and 30 min after the start of internalization, the majority of internalized antibodies (>80%) were localized to early endosomes (Fig. 6).
A majority of internalized radioactivity was lost during the first 3 h of post-incubation.
Only a minor pool of surface-bound CT (∼5%) is transported to the ER; the majority of internalized toxin is instead degraded in the lysosomes [24], [25].
After a 20 min pulse, the majority of internalized endosomes that accumulated Fdex were marked by YFP-Rab7 (Figure 3B), and co-localized with Cy3-mBSA (not shown; [19]).
In agreement with previous report [44], the majority of internalized proteins, including >80% of β1 integrins, recycled back to the surface of the NIH3T3-tTG fibroblasts under these conditions (Fig. 5E).
The majority of internalized scFv 4D5-dibarnase was found in endosomes, presumably from which the IR was released into the cytoplasm where it reached the RNA substrate and caused cytotoxicity.
Afterwards, majority of the internalized nanovehicle will be processed in lysosomes and are eventually released into the cytoplasm (Figure 10d).
These observations are not surprising as the confocal microscopic analysis of protein-transduced cells revealed that the majority of the internalized TN122 protein was localized in vesicles, and only a small proportion was able to escape to the cytosol.
The majority of the internalized LFA-1 left the intracellular compartment during this time period and re-appeared on the plasma membrane as glutathione sensitive LFA-1 (Fig. 1E, lanes 3 and 4).
The cells were then visualized by CLSM, which showed notable separation of green fluorescence (fluorescein-labeled PHLG-TEP) from red fluorescence (Lysotracker Red-stained endosome) after incubation at both 37 and 4 °C, indicating that majority of the internalized polypeptides were not entrapped in the endosomes.
As the majority of this reduced level of internalized LFA-1 is neither in extended nor high affinity conformation and detected with a pan-LFA-1 mAb, it must by default be in the bent, inactive conformation of LFA-1.
