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It was unclear whether the "stop and go" pattern is typical for the majority of injected QD conjugates or if it is only limited to a small subset of QDs.
The liver and spleen uptake were prominent after 4 h post-injection (18.7 ± 1.1, 11.5 ± 0.8%ID/g), indicating a majority of injected NPs are taken up by the MPS.
The majority of injected PulmoBind (~58 %) is retained by the human lung.
131I exhibits differential uptake in the body where the majority of injected activity is taken up by and retained in the thyroid gland [18, 20].
The majority of injected enzyme can be recovered from the liver (≥60%) and smaller amounts in the spleen.
16 In fact, although the majority of injected cancer cells were found to be arrested in the liver sinusoid several minutes after injection, the vast majority of injected cancer cells were disseminated or no longer viable at 24 hours.
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The first in vivo indication of metastasis in any of the D3H1 cohort occurred at week 5, which was 3 weeks later than in animals injected with the same number of D3H2LN cells (Fig. 5), and it took 10 weeks for metastasis to develop in a majority of animals injected with D3H1 cells versus 5 weeks for mice injected with D3H2LN cells.
Overall, as summarized in Table 4, the majority (60 70%) of injected GCase was localized to the liver in either age group.
To analyze the effect of refolded Pgc on CTD Ser 2 phosphorylation, we injected 2 3 hour old embryos and aged them 30 minutes after injection until cellularization was observed in the majority of the injected embryos.
As expected, the majority of embryos injected with Xic1Mo demonstrated a significant decrease in the expression of these markers of cardiac differentiation compared to uninjected and CTRMo injected controls.
The results indicate that, majority of the injected phonons will be scattered by the gold chains, while the electrons can transport smoothly due to the existence of the edge states.
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