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The majority of induced genes in GM05388 cells are also induced in AG09319 cells.
As expected, P3K induced a robust pro-inflammatory gene expression profile in hiDCs, with the majority of induced transcripts involved in mounting an immune response.
Further, the proteolytic cleavage pattern of amphiregulin at the plasma membrane is changed and the majority of induced amphiregulin is released in the cell supernatant, followed by a co-localization with the adhered bacteria at the plasma membrane.
The great majority of induced tumours were adenomas, a minority were carcinomas.
The majority of induced mutations were G/C to A/T transitions.
The majority of induced genes are involved in the formation of secondary xylem, cell wall, lignin, hormone synthesis, and detoxification.
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Majority of chilling induced bZIP genes were also induced by H2O2.
Similarly, the majority of EGF induced genes (86%) is not induced by E2.
Whereas the majority of genes induced by Wy14643 in the liver slices were also induced by Wy14643 in the hepatocytes (Fig. 5a)—as illustrated by the common induction of well-known targets such as FABP1, PLIN2, FADS1 and ANGPTL4 few genes that were downregulated by Wy14643 in liver slices were also consistently downregulated by Wy14643 in primary hepatocytes (Fig. 5b).
In fact, a relatively large group of VvWRKY genes, including VvWRKY08, 14, 16 and 24, was induced since the first hour after the imposition of the stress, whereas the majority of genes induced by salt (SS) and water (WS) stresses, were upregulated after 24 h.
In contrast to the blockade induced by the mGlu5 NAM MPEP, VU0357121 and analogues did not inhibit the effect of glutamate on mGlu5; in fact, the majority of compounds induced a mild potentiation of the EC80 glutamate response.
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