Sentence examples for majority of imprinted from inspiring English sources
In the present study we tried to find any indication of imprinting in chicken, we analyzed the putative differentially methylated regions (DMRs) because the majority of imprinted genes identified so far have differentially methylated alleles [25], [29], and as expected, we did not identify any experimentally demonstrable DMRs in the chicken genome (data not shown).
First, the majority of imprinted genes with weak-to-moderate parental bias are located nearby or at known imprinted clusters, and we show that this localization is evolutionarily conserved, suggesting it is under purifying selection.
While few reports demonstrate genes to be temporally imprinted in the plant embryo (Jahnke and Scholten, 2009; Raissig et al., 2013), the vast majority of imprinted genes has been observed in the endosperm, the ephemeral triploid tissue derived after fertilization of the diploid central cell with a haploid sperm cell.
The majority of imprinted genes were parentally biased in the same manner among all strains.
This is contradictory to the current knowledge that the majority of imprinted genes are maternally hypermethylated.
We find that the majority of imprinted loci remain hemimethylated following reprogramming in both human and chimpanzee iPSC lines.
Using this strategy, we identified the majority of known imprinted ICRs on the array and many novel imprinted DMRs in the genome.
To date the majority of confirmed imprinted genes are situated in the genome in clusters.
The majority of these imprinted genes are found in clusters distributed throughout the mammalian genome, with each cluster containing two or more imprinted genes as well as an imprinting control region (ICR) [ 3].
Monoallelic expression of imprinted genes is controlled by differential methylation at imprinting control regions, (ICRs).
Studies in animals have demonstrated that the progeny of Dnmt3L knockouts exhibit loss of imprinting, stochastic imprinting and biallelic expression of imprinted genes [33], [34].
