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The majority of dose reductions were due to neutropenia or thrombocytopenia.
In contrast, neutropenia accounted for the majority of dose reductions in patients undergoing VC treatment.
The majority of dose postponements were associated with subsequent dose reduction.
The majority of dose delays (from 30%to50%0% for individual studies) were due to logistic reasons or patients wish.
Another option would therefore be to use cumulative incidence of flares as primary outcome, and this is chosen in the majority of dose reduction and discontinuation studies.
The majority of dose reductions were by one level (reduction to 75% of starting dose of fluorouracil and/or of oxaliplatin).
Similar(52)
Similar as those in the other trials, the majority of dose-related grade 3-4 toficities of docetaxel observed in this trial were hematological toxicities.
There seems to be a majority of dose-increases in the placebo group, which might explain the reduction in BP seen in placebo group.
For incobotulinumtoxinA treatment of GFL alone, the vast majority of doses injected were less than or equal to the 20 U standard starting dose recommended in the SmPC.
For vancomycin the majority of doses (40/48; 83%) remained below the BNFC lowest reference independent of the PMA group and variability was highest at <36 weeks of PMA.
Although the vast majority of doses are given at these school clinics, eligible girls may also receive the vaccine through their public health unit or family physician.
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