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Consequently, there was a slight tendency for genes with elevated methylation among individuals to also be differentially expressed, but the vast majority of differential expression did not correspond with altered methylation.
It is clear from the number of genes differentially expressed in PBMC from BTB-infected samples that the majority of differential gene expression occurred early, within 3 h of stimulation with tuberculin antigens.
The majority of differential genes expressed late and transiently.
The majority of differential metabolites was significantly increased in HUPM patients for both urines and serums.
The levels of the majority of differential metabolites were significantly increased in HUPM patients for both urines and serums.
Furthermore, the profile of expression indicated that the majority of differential expression occurred between 0 h and 12 h in PBMC from the control animals (Fig. 2b).
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In addition, this study reported a strong co-regulation of miRNA genomic clusters and showed that for the majority of miRNAs differential expression cannot be attributed to chromosomal loss or gain in their genomic region.
The majority of the differential genes (i. e. those with greater distance to the plot center) correspond to this difference.
This may suggest that the vast majority of the differential expression is due to the E. coli infection of neighbouring quarters.
A majority of the differential chromatin marks are also suggestive of increased levels of viral infection in the susceptible line symptomatic of lowered immunocompetence in these birds at early stages of the disease.
The majority of the differential protein spots (28 out of 50) showed significant differences between genotype pools CIS-t and CIS-s before the onset of cold treatment (Table 2, Additional file 4: Table S4).
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