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In contrast, our data challenge the paradigm of gradual evolution, showing that the majority of copy number aberrations are acquired at the earliest stages of tumor evolution, in short punctuated bursts, followed by stable clonal expansions that form the tumor mass.
Parental and PPP tolerant cell lines were identical in the majority of copy number aberrations detected.
The fine-scale structure of the majority of copy number variation (CNV) regions remains unknown.
The vast majority of copy number aberrations of 22q in meningiomas point to inactivation or a decreased gene dosage.
Low copy number gains (one to two additional copies) represented the vast majority of copy number alterations at 1q and 8q24 (80%and78%78 %, respectively).
These included seven genetically-diverse pancreatic cancer cell lines that together harbor the vast majority of copy number alterations from which the 185 genes were selected.
Similar(49)
Thus the vast majority of copies traverse only a few nodes.
To be clear, inauthentic objects represent a small percentage of the Smithsonian's and National Gallery's immense holdings, and the overwhelming majority of copies are labeled as inauthentic.
Midweek will be more traditional, in a 'Sport' sort of way". The Sunday Sport is on newsagents' shelves until Tuesday, although the vast majority of copies are sold on Sunday.
Indeed, only infrequent full-length or near full-length units of LINEs or LTR transposons are long enough to have a high probability of occurrence of FRT-like sequences (Figure 5), while the majority of copies of LINEs are shorter than 1 kb and SINEs are only 100 400 bp long [24].
Conversely, the majority of copies of the 6.1-kb sequence exist on chromosomes carrying more than one copy (fig. 2).
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