The vast majority of cellular decisions derive from specific protein-protein interactions.
G protein-coupled receptors (GPCRs) mediate the majority of cellular responses to hormones and neurotransmitters.
G-protein-coupled receptors (GPCRs) are the largest family of eukaryotic plasma membrane receptors, and are responsible for the majority of cellular responses to external signals.
This temperature provided a suitable window between unbound and agonist-bound AR where the majority of cellular AR was thermally destabilised in the absence of agonist target engagement (Fig. 2a).
Hitherto regarded as specific elements of confined niches, we demonstrate that CARcs and SECs are spatially dominant and available for physical contact with virtually all, or the majority of cellular elements in BM.
Kinases are among the most studied drug targets in industry and academia, due to their involvement in a majority of cellular processes and, upon dysregulation, in a variety of diseases including cancer, inflammation, and autoimmune disorders.
The stearoyl-acyl-carrier-protein (ACP) desaturase is a plastid-localized enzyme that catalyzes the conversion of stearoyl-ACP to oleoyl-ACP and plays an important role in the determination of the properties of the majority of cellular glycerolipids.
The majority of cellular response overview genes were attributed to biotic stress (934 genes), abiotic stress function (361), redox (209) and cell division (200) (Fig. 2d).
The mitochondria provide for the majority of cellular energy to the heart and are dependent upon a continuous supply of oxygen delivered by the coronary arteries to maintain the energy requirements of the myocardial cells.
At 3.5 hpi of both Set 1 and Set 2, when the viral RNA amounts were still low, EV71 RNA exhibited significantly higher relative translation efficiency than the majority of cellular mRNAs of both mock- and EV71-infected cells.
The majority of cellular ATP is generated by this process.
