Sentence examples for majority of breakpoints from inspiring English sources

The majority of breakpoints were unique except for two cases, both T-ALL, showing identical deletions.

The vast majority of breakpoints therefore apparently seemed to remove more than two-thirds of the mitochondrial genome.

The vast majority of breakpoints would be consistent with deletions eliminating more than two-thirds of the mitochondrial genome (Fig.  5A, grey arrows) and would remove the OL replication origin.

The 414 unique fragments correspond to 378 introns and 36 exons, confirming that the vast majority of breakpoints (91.3%) are located within introns and that translocations very rarely disrupt exonic sequences.

In addition, the majority of breakpoints in a papillary thyroid carcinoma rearrangement mapped to fragile sites occur at microhomology patches, indicating that fragile site-associated rearrangements can also arise by microhomology-mediated SSA [ 42].

Gene fusions in samples with the neural subtype have a broader chromosomal distribution, with the majority of breakpoints on chromosomes 3, 2, 7, 6, 1, 15, 4 and 12.

Interestingly, we found that the majority of the breakpoints occurred in regions that shared the same state of replication timing (Supplementary Figure 14b).

The majority of intragenic breakpoints we identified were associated with gene disruption.

This is further supported by our observations showing that the majority of chromosomal breakpoints are shared between distinct clones within a particular biopsy.

Although the majority of such breakpoints have been assigned to cytogenetic bands, they have not yet been mapped with any degree of precision.

Although the great majority of these breakpoints are located within a segment of about 100 bp located around the MTC, there are still some cases with breakpoints out of the MTC [ 20].