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These algorithms are however inadequate for capturing NFRs for the following reasons: first, as most TFs are sparsely localized across the genome, many algorithms for identifying TF binding sites (TFBSs) are designed under the assumption that TF binding is an uncommon event, thus the majority of array data is considered background noise.
Examining patterns of gene expression in females (either juvenile or mature) compared to males reveals that the majority of array elements show some degree of sex-biased gene expression (Fig. 1).
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In concordance with the MAQC established framework [38], designed to increase the consistency of microarray datasets, the majority of arrays in this study cluster within 2 standard deviations when assessed by quality metrics (Figure 8 A).
We could see several clones with extreme values in the majority of array-CGH profiles, which needed more detailed investigation.
However, the vast majority of array-based SNP genotyping approaches are not available for non-model species and become prohibitively expensive for screening large numbers of individuals which is commonly required for dissecting of the molecular genetic basis of phenotypic traits.
For a given probe set, the same probe had the greatest fluorescence intensity in the majority of arrays.
A score of 0 in the final pathprint vector represents pathway expression at a similar level to the majority of arrays of the same platform in the GEO database, while scores of 1 and -1 reflect significantly high and low expression respectively.
The most common approach to quality assessment of microarray results makes the assumption that the majority of arrays in each dataset is of good quality, and various parameters serve to identify outlier arrays (Beisvag et al., 2011; Bolstad et al., 2005).
One well-known fact is that the majority of the array surface experiences very thick turbulent boundary layers (TBL) and large Reynolds numbers.
The majority of exon array probesets contain four probes.
The majority of the array content (53%) was derived from cDNA sequencing.
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