Sentence examples for majority of administered from inspiring English sources
It was assumed for our computations that the majority of administered drug was recovered in the urine and that the major metabolic pathways were within linear ranges because the achieved maximum plasma concentrations (~5 mg/l (33 µmol/l) were well below the reported Km values of the contributing metabolic enzymes.
As this corresponded to the majority of administered 124I-IAZGP, the conservative assumption was made that the pharmacokinetics of urinary clearance was identical to the bi-exponential whole-body clearance, and these parameters (fractions and biological half-times) were used in the voiding bladder model of OLINDA/EXM.
Systemic intravenous delivery (through the tail vein in most rodent studies) was the route that was most supported by evidence, despite the fact that the majority of administered cells appear to be trapped in the lungs (Fischer et al., 2009).
Our results show that within the first 12 h after the administration of 177Lu-PSMA-617, the majority of the administered activity is excreted (approximately 70 ± 7%).
After oral administration, only a minute amount of CUR appears in the blood circulation; the majority of the administered CUR was excreted in its simplest form in the feces.
The majority of orally administered drugs are described to be passively transported across the lipophilic cell membranes [Lennernäs, H. et al. (1994) Intestinal drug absorption during induced net water absorption in human; a mechanistic study using antipyrine, atenolol and enalaprilat. Br. J. Clin. Pharmacol.
The majority of the administered drug is excreted unchanged in the urine via active tubular secretion.
The majority of cells administered were both V γ9V δ2 TCR positive and CD4CD8 double negative.
This finding provides an explanation to a previous research finding that reported a majority of caretakers administered AL to their children without food [ 11].
As noted by the authors, the majority of the administered nanocapsules reach the target site with minimal amounts accumulated in the liver and spleen.
As the majority of studies administered filgrastim and lenograstim for 10-14 days (for 3-week chemotherapy cycles), there was insufficient data to assess the effects of shorter durations of G-CSF treatment.
