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RNA and DNA profiling identified major variability between retinoblastomas.
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Such study would necessary need a full view of the mtDNA diversity since the study of few selected loci might underestimate major variability within and between isolates.
But major variability can occur even for biologic questions.
We found that major variability was related to the anticyclone.
The ICC is the ratio of the between-women variability to the total variability (between- plus within-woman variability).
Furthermore, the format of the assessment instrument was identified as a major source of variability between study outcomes.
Oomen et al. concluded that gastric simulation pH was the major source of variability between the results of a round robin test of five in vitro models [82].
Additionally, due to the small number of replicates, we decided to apply the dye swap design to minimize the gene-specific dye bias [ 44], which is the major source of experimental variability between replicates.
To take into account the phylogenetic relationships (population structure) between the strains under consideration in the coevolutionary cluster analysis, we identified major components responsible for variability between strains using principal component analysis, and adjusted the evolutionary rate for these components prior to coevolutionary gene cluster analysis.
Both AB01-01 and 329 primers produced considerable genetic variability between L. major isolates from different regions of Tunisia as well as within the same regions.
However, to estimate the variability in the amount of genetic divergence between populations due to historic processes we conducted coalescent simulations implementing parameters from a recent calibration of the method shown to accurately recreate the patterns of genetic variability between the three major world populations used here [12].
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