Sentence examples for major unsolved elements from inspiring English sources

As oligomers may exert effects distant to the place of their generation, they offer a convenient explanation for one of the major unsolved elements in the amyloid cascade hypothesis: the spatial separation of initial amyloid deposition and tau pathology in the brain.

But making them in quantity is a major unsolved challenge.

It also doesn't reconcile quantum physics with relativity, whose fundamental incompatibility is a major unsolved problem in physics.

For scientists, however, Basque is a major unsolved mystery.

One major unsolved problem with our solution is related to searching and indexing.

This had been a major unsolved problem in number theory for decades.

Cut-out complication remains a major unsolved problem in the treatment of trochanteric hip fractures.

The review concludes with a brief summary of major unsolved questions concerning this very small, yet potentially complex magnetosphere.

To write that our understanding of the origin and early evolution of life faces major unsolved problems is an understatement.

Conversion of lignin into renewable chemicals is a major unsolved problem in the development of a biomass-based biorefinery.

Current high levels of public and private debt together with still weak bank balance sheets are a major unsolved problem.