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The ubiquitously expressed RFC is the major transporter for folates in mammalian cells and tissues.
Serum albumin is the most abundant of the proteins in blood plasma and is the major transporter for delivering several drugs in vivo.
Human serum albumin (HSA) is the most abundant of the proteins in the blood plasma and is major transporter for delivering several drugs in vivo.
The ApoE protein also functions as a major transporter for the Aβ proteins [ 6].
RFC (reduced folate carrier) is the major transporter for reduced folates and antifolates [e.g. MTX (methotrexate)].
ABCG2 is a major transporter for MTX that can be directly inhibited by DEX and MPRED, but apparently not by prednisolone (Pavek et al, 2005).
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Major transporters for sulfate (SULTR3 1) and borate (BOR2) were found in this specific cluster, together with AtALMT1 and other organic molecule transporters [e.g. mannitol and the organic cation/carnitine transporter (AtOCT1)].
RFC is also a major transporter of antifolate drugs used for cancer chemotherapy such as MTX (methotrexate), pemetrexed and raltitrexed [ 4].
Selenoprotein P is the major transporter of selenium, a trace element required for normal development [20].
For Tenneco, a large and diversified industrial company, the sales mark a rapid and decisive march out of the oil patch as a producer, but the company will continue as a major transporter of natural gas.
A major transporter of Mn in mammals is the divalent-metal transporter (DMT1).
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