Sentence examples for major toxicity associated from inspiring English sources

There was no major toxicity associated with nortriptyline, but dry mouth, dizziness, and constipation were more common with nortriptyline.

Myelosuppression is the major toxicity associated with bendamustine.

We did not find any major toxicity associated with GCV treatment.

The major toxicity associated with docetaxel is highly predictable myelotoxicity (Posner, 2001a).

The major toxicity associated with this regimen was myelosuppression: a grade 4 neutropenia was observed in 11% of the courses in group B and in 47% of the courses in group C; no grade 4 neutropenia was observed in group A. No grade 4 thrombocytopenia or anaemia were observed.

6, 7 In that study, the major toxicities associated with weekly nab-paclitaxel were myelosuppression and peripheral neuropathy.

The combination of CTLA-4 and PD-1 blockade may also enable more persistent immune activation while avoiding the major toxicities associated with HD IL-2.

Hematologic toxicities were the major type of toxicity associated with tivantinib in Japanese patients with advanced HCC.

We can use the computational model to quickly and systematically test a large number of regimens and quantify improvements that are achievable, acknowledging two major obstacles: drug toxicity associated with increased cumulative exposure to antibiotics, and patient compliance and implementation issues associated with directly observed treatment.

Importantly, thrombocytopenia, which is the major dose-limiting toxicity associated with HDACi, in mice receiving the combination of panobinostat and ATO, was similar during the course of therapy to that of mice receiving panobinostat alone (see Additional file 1: Figure S1B).

Although the radicals in gas-phase smoke have a very short life span, 21,23,24 a wealth of evidence supports the notion that a major part of the toxicity associated with CS is related to oxidative stress caused by reactive oxidants and radical species in tobacco smoke itself or by secondary oxidative events, such as lipid peroxidation activated by smoke exposure.