Sentence examples for major therapeutic problem from inspiring English sources

The high recurrence rate, and in particular the high local recurrence rate, constitutes a major therapeutic problem for the Korean population, yet there is a paucity of reports addressing the independent predictors of response and survival rate of OSCC in Korea.

In burn wound care, bacterial infection remains a major therapeutic problem and renders large numbers of thermal injuries virtually untreatable.

Multiresistant pathogens are a major therapeutic problem [ 22].

Polymicrobial invasive infections represent a major therapeutic problem.

Treatment of early and multiple unresectable cutaneous recurrences of melanoma is a major therapeutic problem.

Relapses of P. vivax malaria are a major therapeutic problem, particularly after primaquine therapy.

Patients with cirrhosis and impaired coagulation often pose major therapeutic problems during bleeding episodes or invasive procedures.

MDR K. pneumoniae strains have caused major therapeutic problems worldwide.

One of the major therapeutic problems is that tumors initially responsive to chemotherapeutic approaches can progress to more aggressive forms poorly responsive to therapies.

Low-back pain is a major diagnostic and therapeutic problem, which causes a great deal of suffering and is a major expense to society [ 1, 2].

The dissemination of ESBL-producing Enterobacteriaceae in the hospital setting is a problem with major therapeutic and epidemiological consequences [ 11].