Sentence examples for major target site from inspiring English sources
The NA glycoprotein is not the major target site for neutralization of the virus by antibodies.
The microcirculation represents the major target site of ischemia reperfusion (IR) injury [ 30– 30].
GluCl, considered to be the major target site of AVM drugs in invertebrates, displayed similar mRNA expression levels in EMB-resistant and reference strains.
Although the DA transporter is a major target site of amphetamine (Madras et al. 2005), dopamine D3 receptors in the ventral striatum also regulate the sensitivity to the locomotor-stimulating effects of amphetamine (McNamara et al. 2006).
Nevertheless, pharmacokinetic studies with nanoparticles encapsulating Pt revealed prolonged persistence in systemic blood circulation and decreased accumulation of Pt in the kidneys, a major target site of cisplatin toxicity.
Taken together these data confirm that like TPβ, TPα is subject to near complete and sustained agonist-induced homologous desensitization while, consistent with previous reports [50], TPΔ328 undergoes partial and transient desensitization suggesting that the major target site(s) involved in homologous desensitization of TPα may be located within its unique C-tail domain.
Our analysis identified S17 and T21 in BMAL1 as major target sites for GSK3β- mediated phosphorylation.
These intercellular contacts appear to be the major target sites of vesicular traffic that involves synaptic components [ 132].
Pharmacokinetics studies with [Pt(O,O′-acac)(γ-acac)(DMS)] revealed prolonged Pt persistence in systemic blood circulation and decreased nefrotoxicity and hepatotoxicity, major target sites of cisplatin toxicity.
The detailed analysis of the S1 S5 phosphosites in in vitro phosphorylation experiments and in oocyte auxin transport experiments revealed that PIN1 S4 as well as PIN3 S4 and S5 are major target sites for D6PK.
We cloned partial fragments of the two major target sites of insecticides used in malaria control, the acetylcholinesterase gene (AChE) which is the target site of carbamate and organophosphate insecticides and the voltage gated sodium channel gene (kdr) which is the target site of pyrethroids and DDT.
