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The major target organs include the lungs, liver, mediastinum, omentum and heart [ 8].
The liver, lungs and lymph nodes are major target organs for metastases of diverse cancers in men.
A comparison of the major target organs affected by chemicals carcinogenic in both species revealed that 64% of the chemicals studied produced cancer at the same site.
Histological examination of other major target organs, which can be damaged by chemotherapy, including the spleen, kidney, liver, or heart, failed to show any gross pathology in any of the treatment groups.
One of the major target organs in SLE patients is the kidney, and LN is the most common types of secondary glomerular diseases and frequently seen in females [ 62, 63].
The liver is one of the major target organs of TH, and TH levels are closely correlated with multi liver-associated diseases within a spectrum ranging from hepatic steatosis to HCC [ 23, 111, 115].
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The major target organ that was highly affected is the tegument and suckers that damages were observed by LM and SEM.
The human exposure to ZnO NPs is undeniable, and it established that major target organ for ZnO NPs is the liver.
As liver is the major target organ for metabolic adjustments, we exploited a selective transcriptomics approach to address molecular response in this tissue during acute stress adaptation in rainbow trout.
The liver is a major target organ in severe cases of dengue infection [7], [16], [41].
The liver plays a critical role in metabolism, serum glucose and lipid regulation and is a major target organ of TH.
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