Sentence examples for major target genes from inspiring English sources

c qRT-PCR measurement of mRNA transcripts for hsf-1 and its major target genes hsp-12.6, hsp-16.2 and hsp-70.

The computational approaches undertaken in these studies are effective in dealing with the multiple complex data to indentify major target genes and transcriptional themes, and justified by the results being frequently supported by existing experimental data.

SIRT1 and Bcl2 are two major target genes suppressed by miR-34a [ 17, 26].

ZEB1 is a transcriptional repressor, and some of its major target genes, the miR-200 family, have been linked to chemosensitivity.

Vascular endothelial growth factor (VEGF) is one of the major target genes for HIF-1 α that directly participates in angiogenesis and a recognized therapeutic target [ 22, 23].

Major target genes of NF-κB include adhesion molecules (VCAM-1, ICAM-1, E-selectin), cytokines and chemokines (Hayden and Ghosh, 2004).

The recently described Bcl10 gene has been suggested to be a major target gene for inactivation in a variety of human cancers.

CEACAM6 is also a major target gene for Smad3-mediated TGF-β signaling [52].

The major target gene of p53 upon γ-irradiation-induced DNA damage in the liver is p21, which is required for cell cycle arrest and DNA repair [25].

After microarray analysis, we found LITAF as a major target gene of KKv1.

In this study, we applied the YTH approach to three major target gene groups.