Sentence examples for major substrate of from inspiring English sources

Jia, G. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.

Downregulation of ACE2 may result in the elevated plasma level of Ang II, which is a major substrate of ACE2.

Jia, G. et al. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.

Jia G, Fu Y, Zhao X, Dai Q, Zheng G, Yang Y. et al. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.

Using display PCR, we found that acquisition of resistance to the multinuclear platinum complex BBR3464 was associated with modulation of several transcripts, including up-regulation of the major substrate of protein kinase C (PKC), the myristoylated alanine-rich C kinase substrate (MARCKS).

It is concluded that the Rh polypeptide is fatty acid-acylated, being a major substrate of an acylation-deacylation mechanism associated with the erythrocyte membrane.

However, target-mediated toxicity of β-secretase inhibition cannot be ruled out, as long as the major substrates of this enzyme are unknown.

The mammalian FoxO family of transcription factors FoxO1, FoxO3a, and FoXO4 are major substrates of the protein kinases PKB (Akt).

The changes in actin and tubulin, the major substrates of CCT [16], at low temperature have been investigated in several species of plants and animals.

Surprisingly, ERK activation was not accompanied by increased phosphorylation of MSK1 or MSK2 (data not shown), two major substrates of ERK critically involved in histone H3 phosphorylation [24], [25], [26].

This process requires four heterooligomeric protein complexes (ESCRT-0, -I, -II, -III), collectively termed the ESCRT machinery [8], [9], that facilitate the trafficking of mono-ubiquitylated proteins, the major substrates of the MVB pathway [5], [8], [10].