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Discover Ludwig"major struggle" is a correct and usable phrase in written English.
You can use it to refer to a large, difficult problem or challenge that one is facing: I'm having a major struggle to keep up with my studies and work at the same time.
Exact(44)
We still have a major struggle ahead.
Today, finding support for AIDS research remains a major struggle.
Beauty usually won, but only after a major struggle.
"In every other recession it was a major struggle to extend unemployment benefits.
Leaving my flat became – if not a major struggle, then certainly effortful.
'The fact that Ray Charles didn't have his eyesight - that's not even my major struggle,' adds Foxx.
Similar(16)
One of Bian Qiao's major struggles was against superstition.
One of Zook's major struggles was the off-field responsibilities.
Murray major struggled on his serve, but his brother brought an air of stability.
"Unfortunately, there's a clear recognition that there's some major struggling going on here," Cashman said.
The general election ballot is reserved for major struggles; it is not a forum for continuing intraparty feuds.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com