Sentence examples for major structural role from inspiring English sources

Clathrin, coupled to the membrane by adaptor proteins, is thought to play a major structural role in endocytosis by self-assembling into a cage-like lattice around the forming vesicle.

Dystrophin and the DAPC play a major structural role in muscles by forming a link between the internal cytoskeleton actin and the extracellular matrix, but the DAPC also has important signalling functions via other components (24, 25).

The presence of nuclear lamins supporting the nuclear envelope as well as dispersed throughout the nucleus suggests that these proteins may play a major structural role as a part of the nuclear scaffold/matrix.

Not only do these play a major structural role in both unicellular and multicellular eukaryotes, but they are also important in the defense against parasites or interactions of parasites with their hosts.

Pol ε plays a major structural role during DNA replication, as part of the Pre-LC that is so critical for initiating DNA replication and, with Pol α, a part of the core replication fork machinery.

As an extracellular matrix (ECM) protein, MATN3 was thought to play a major structural role in forming a filamentous matrix network by interacting with collagen fibrils, multiple proteoglycans, and other glycoproteins [ 5].

This is not surprising because these proteins have major structural and functional roles in human serum.

Owing to the major structural and functional roles of GPCho and GPEtn in T. brucei, disruption of their biosynthetic pathways is likely to interfere with the parasite biology in multiple ways and thus the enzymes involved become of interest as possible novel targets for chemotherapy.

Network analysis also highlighted the structural role of major stress related metabolites, e.g., Pro, quercetin and ascorbate, which drastically altered their connectedness in the Shiraz network under water deficit.

In modern chordates, the notochord is a major structural support and plays a role in locomotion by stiffening the body and assisting the antagonistic action of the muscles to generate lateral propulsive movements.

They have a structural role, and the structures of individual connective-tissue polysaccharides are related to specific animal functions; hyaluronic acid, for example, the major component of joint fluid in animals, functions as a lubricating agent and shock absorber.