Sentence examples for major structural domains from inspiring English sources

All three known HSL isoforms exhibit a homodimeric structure with a head-to-head orientation of the two monomers, and with two major structural domains in each monomer.

It contains three major structural domains: a small N-terminal domain (NTD), a catalytic domain (CAD) and a large C-terminal domain (CTD).

Seven immunologically distinct neurotoxins, produced by strains of Clostridium botulinum, are most potent of all toxins (for a review see references [1], [2]. Botulinum neurotoxins (BoNTs) are composed of three major structural domains of approximately equal size of 50-kDa each.

The three-dimensional structure has not been solved for any of the HSL isoforms, but several studies suggest a domain organization with two major structural domains, a 48 kDa C-terminal domain containing the active site in an α/β-hydrolase fold [7], [8], [9] and a 36 kDa N-terminal domain of HSLadi that has been shown to complex with fatty acid binding protein [10], [11].

LAM molecules have three major structural domains.

The E-cadherin glycoprotein is composed of three major structural domains: a single transmembrane domain, connecting with a cytoplasmic domain, and an extracellular domain comprising five tandemly repeated domains called EC1 EC5, which are exclusive to cadherins [ 17].

Here, we report the crystal structure of the major structural domain of Cj0977, which reveals a homodimeric "hot-dog" fold architecture.

Insight into the (enzyme-catalysed) modifications of homogalacturonan, the major structural domain of this polysaccharide which strongly influences the pectin structure function properties, can be obtained by in situ research tools.

PolyADP-ribose polymerase-1 is composed of three major structural and functional domains: a DNA-binding domain, an automodification domain and a catalytic domain (Kraus, 2008).

In the eukaryotes there also appears to have been a derivation of at least two domains, namely the POZ and WWE domain through major structural modification of the core β-GF domains.

The structure of the rabphilin C2B domain showed that a major structural difference between the C2A and C2B domains of tandem C2 domain proteins is the presence of helix HA at the bottom of the β-sandwich [18].