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To examine risks for major structural birth defects in infants after first trimester inactivated influenza vaccine (IIV) exposures.
In brief, the NBDPS is a population-based case control study of major structural birth defects.
Control infants (live-born infants without major structural birth defects) were randomly selected from birth certificates or birth hospitals, depending on study site.
Paternal exposure to FA and effects on reproduction was evaluated in a case control study, where endpoints were time to pregnancy (TTP), spontaneous abortion, preterm birth, sex ratio and major structural birth defects (Wang et al. 2012).
In the United States, the Centers for Disease Control and Prevention CDCC) estimates 3% of children born each year have a major structural birth defect that appears by the sixth birthday.
It is limited in geographic coverage, including residents of just five central-Atlanta counties, but it conducts active surveillance of major structural birth defects through doctors' offices, clinics, and genetic laboratories rather than relying on hospital birth records, which is a limitation of some registries.
Similar(54)
The cohort included singleton non-Hispanic African-American, non-Hispanic Caucasian, and Hispanic infants who reached at least 37 weeks of gestation and were born between 1 January 1994 and 31 December 2004 without major structural congenital birth defects (n = 417,280).
We sought to examine the association between increased first-trimester fetal nuchal translucency (NT) measurement and major noncardiac structural birth defects in euploid infants.
Between three and six of every hundred babies born have a major structural malformation; other babies have very low birth weight, which predisposes them to health problems; still others die in utero and others have significant mental or other functional deficits, without necessarily having obvious structural defects.
Major structural congenital anomalies are diagnosed in 2 4% of births, but in most cases their etiology remains unknown (Weinhold 2009).
Approximately 3percentt of 134 million annual births around the world are affected by a major structural disorder, a congenital abnormality [ 3] while the percentage of that varies among countries and regions [ 2- 7].
Related(16)
severe structural birth
major adverse birth
major structural damage
major structural investment
major unrelated birth
major structural reorganisation
major structural difference
major structural upheaval
major structural work
major structural reform
major structural overhaul
major structural material
major structural protein
major structural change
major structural component
major structural obstacle
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