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A potential major source of discrepancy between studies was the method of screening for G6PD deficiency.
A major source of discrepancy is the definition of TF itself.
Thus, there is some degree of functional redundancy, although it is also not the major source of discrepancy between TF binding and effect of the TF deletion.
Therefore, the major source of discrepancy is not the estimated cancer mortality distribution but the overall mortality envelope applied to each region.
These figures and especially those from the 1984 study are considerably higher than the ones reported in the present study, but the different instruments and sampling frame are probably the major source of discrepancy.
While Landry et al. considered pharmaceutical costs, and this study did not, this is not anticipated to be a major source of discrepancy as they comprised a relatively minor proportion of overall medical costs (approximately 1-21-2% 18].
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This consistency is important if one keeps in mind that differences in data selection are acknowledged to be one of the major sources of discrepancies between main field models yet parameterized in similar ways (e.g., Finlay et al., 2010).
These results indicate that route of administration is not likely the major source of the discrepancy between findings from animal and human studies of nicotine administration.
These tumors, which represent 30 60% of cases, are a major source of inter-observer discrepancy and may display intermediate phenotype and survival, making treatment decisions for these patients a great challenge, with subsequent under- or over-treatment.
Indeed, clinicians face a huge problem with respect to patients who have intermediate-grade tumors (grade 2), as these tumors, which represent 30% to 60% of cases, are the major source of inter-observer discrepancy and may display intermediate phenotype and survival, making treatment decisions for these patients a great challenge, with subsequent under- or over-treatment.
Based on the amount of discrepancy between our analyses before and after removing ambiguous sequence reads, mapping artifacts appear to be a major source of potential bias for insertional mutagenesis screens.
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