Sentence examples for major snare from inspiring English sources

Comparative genomics and molecular phylogenetics have shown that the four major SNARE super-families (see [ 6] for a recent update on SNAREs classification) were already present in the Last Common Eukaryotic Ancestor (LCEA) [ 7].

Brevins seem to be absent from the L. major SNARE repertoire, as indeed they are from Plasmodium falciparum and Arabidopsis thaliana [ 25].

Analyses of SNARE [ 10- 12] and Rab [ 13] sequences are consistent with each family having evolved from an ancestral gene, which then gave rise to the major SNARE and Rab gene families present in extant eukaryotes.

A similar series of helixes could as well be unambiguously predicted in sequences from L. major SNARE members of the Qb and Qc groups (see Additional file 2 and Figure S2 of Additional file 1).

The analysis of the SNARE domain allowed us to classify L. major SNAREs into groups, but that is not sufficient to assign a function and a localisation to each individual SNARE.

List of identified putative L. major SNARE-interacting orthologues with their BLAST E value and their predicted size in amino acids (AA).

Our bioinformatic analysis of the predicted L. major SNAREs indeed reveals some peculiarities.

Another characteristic feature identified in L. major SNAREs was found in the members of the R group.

When putative homologues of the L. major SNAREs were searched for using BLAST, the returned results yielded E values generally higher than 10e-20 (see Additional file 2).

This study also presented the intracellular localisation of the L. major SNAREs from the Qa group and reveals that these proteins could be useful as organelle markers in this parasitic protozoon.

For example, the major Qa/syntaxin SNARE families are present in most eukaryotic genomes and likely each evolved via gene duplication from a single ancestral syntaxin before the existing eukaryotic groups diversified.