Sentence examples for major signalling pathway from inspiring English sources

Our study now provides evidence that in vivo and in vitro the number of VPC is reduced in conditions of type 2 diabetes and that one major signalling pathway involved is the activation of the transcription factors ETS1 and ETS2.

PKA mediates a major signalling pathway that is crucial for linking stress responses and cell proliferation.

The Jak/Stat pathway represents a major signalling pathway that enables a cell to interpret and react to inflammatory signals and cytokines (Leonard and O'Shea, 1998).

The present study identifies the PI3K mTOR axis as a major signalling pathway that controls MCF-7 cells' phenotypic changes that include lipid synthesis.

Phosphoinositide 3-kinase, a lipid kinase that integrates different signals to balance survival and apoptosis, represents a major signalling pathway for cell proliferation.

One major signalling pathway towards mitochondrial dysfunction involves the inhibitor of cyclin-dependent kinases p21 (CDKN1A), which is activated by the DDR and triggers via GADD45 the induction of p38MAPK and TGFβ.

Of the 25 HG, eight encode key components of two major signalling pathways: Wnt and TGF-Beta.

The nervous and endocrine systems are major signalling pathways between external cues, such as the ambient temperature, and internal physiology responding to environmental changes [7].

Inhibition of major signalling pathways and microtubule polymerization.

Cells undergo apoptosis through one of the two major signalling pathways.

We also investigated major signalling pathways involved in NRP-1 and VEGF induction by EGF.