Sentence examples for major sequence variants from inspiring English sources

Two major sequence variants of the minicircle have been described and here we have sequenced the type B variant and designed a specific PCR test to distinguish it from type A. Further a test based on maxicircles to distinguish T. brucei brucei from T. evansi was designed and evaluated.

In addition, the major sequence variants hKY04-1 and 04-7, detected in commercial hop gardens in 2004, were found to be identical to HpSVd-grapevine and its U25-deletion mutant hAIw36, respectively.

The analysis was performed for oligonucleotides of length k = 17 or 20 and reconstruction of major sequence variants was done using a minimal seed k-mer frequency of 0.0001 and extension threshold of 10%.

Of the seven major MPER sequence variants we identified in subject-pairs 12 and 16, four of them had substitutions at position 683 that eliminated the CRAC motif (K683Q), yet were functional and represented significant portions of those subject's quasi-species.

Three splice variants showed major sequence differences in exon 2. The other three are minor variants of the other three major variants that differ in three nucleotides in exon 4. All transcripts express essentially the same protein that harbors a RBD flanked by two RS-rich domains but differ in the length in the first RS domain (RS1).

Among the 17 major sequence groups of ospC, 2 minor sequence variants of major-group allele B were geographically distinct and thereby named B1 in North America and B2 in Europe.

This procedure should not only rigorously identify specific clones, but it could also uncover amino acid sequence variants of major muscle proteins such as the troponins1 6.

The element MtPH-M-3-VI showed apparently a mosaic structure, as it contained the 3' subterminal region from lineage I, while the major portion of the element contained sequence variants chracteristic for the lineage II.

High throughput technologies and more sensitive mutation detection systems in the DNA diagnostic laboratories have led to an increasing number of sequence variants in the major cancer-predisposing genes for which the clinical significance is unknown.

A majority of the samples only contained one major HpSVd variant, but some contained multiple sequence variants.

At positions where sequence variants were observed, the major allele was considered as the reference allele.