The carboxyl terminus of Rap1p, the major sequence-specific telomeric binding protein, interacts with both Sir3p and Sir4p, while Sir4p interacts with Sir2p (Moretti et al. 1994; Moretti and Shore 2001).
Tardigrade genomes invest in stress-specific adaptations, this includes major sequence related protein clusters, functional clusters for stress as well as specific regulatory elements in mRNA.
(5) According to a recent study, if a protein binds to the major groove, it should associate with DNA in a sequence specific manner [38] [40].
MicroRNAs (miRNAs) are a major class of endogenous short non-coding RNAs that post-transcriptionally modulate gene expression in a sequence specific manner [ 10].
Each spray has a special DNA sequence specific to the store where the system is installed.
By using this approach, we decomposed influences on DNA replication time into two major components, a sequence-specific one and a sequence-independent one.
Although RdDM is known to be a major coordinator for sequence-specific de novo methylation in plants [37], alternative mechanisms probably exist because a certain number of methylated regions are not associated with siRNA expression in the Arabidopsis genome [9].
Many proteins interact in the space of the major groove, where they make sequence-specific contacts with the bases.
Combining the three GO major subcategories, specific expression sequences were mainly involved in the stress response of the nutrient reservoir and abiotic/biotic stimulus.
A major type of regulatory proteins is sequence-specific DNA binding transcription factors (TFs), which modulate expression of their target genes by binding to short DNA segments called transcription factor binding sites (TFBSs) (1).
In addition, SimR makes a number of sequence-specific contacts to the major groove via its helix-turn-helix motif.
