Sentence examples for major selective substrate from inspiring English sources

Notably, the level of p62, a major selective substrate for autophagy that is incorporated into autophagosomes through direct binding to LC3, was decreased with sorafenib treatment.

There are six major MAP2Ks responsible for MAPK phosphorylation, but each has selective substrate specificities.

The psychostimulant methylphenidate (MPH) was chosen as an hCES1 selective substrate.

The published analysis of non-response revealed no major selective health-related factors [24].

Moreover, we observed that p62/SQSTM1, a selective substrate of autophagy, decreased in rasfonin-exposed cells.

P62 is a protein known to be a selective substrate for degradation during autophagy.

The assay has been carried out as described in Lahm et al (2007) on the trifluoroacetyl lysine substrate or on the HDAC6 selective substrate (Heltweg et al, 2004).

(B ) The binding of the MRE β-loop serves as an additional checkpoint for substrates with a small periplasmic region and contributes to selective substrate cleavage.

In evolutionary and conservation biology, parasitism is often highlighted as a major selective pressure.

Drought is a major selective constraint in the evolution of plants.

Thus, QACs may act as major selective agents for promotion of class 1 integrons [ 32].