Sentence examples for major segregation defect from inspiring English sources

Instead, premature separation of dyads in meiosis II was the major segregation defect in aged eggs and these were associated with very low levels of SGO2.

Anaphase lagging chromosomes are a major source of aneuploidy in normal vertebrate cells (Cimini et al., 2001) and the main type of chromosome segregation defect observed in CIN cancer cells (Thompson and Compton, 2008; Bakhoum et al., 2014).

Despite this segregation defect, the mother's cytoskeleton was completely disassembled in every budding round.

The alp5-1134 mutalsoalso causes a chromosome segregation defect that results in activation of spindle checkpoint in mitosis [56].

Thus, a defect that occurred in meiosis I is read out as a segregation defect in meiosis II.

This gross chromosome segregation defect ultimately results in highly penetrant embryonic lethality.

Genome duplication could be caused by DNA re-replication, a chromosome segregation defect, or improper cytokinesis [ 50].

As Cse4 is required for centromere function, it might be anticipated that snf2 mutant strains display a chromosome segregation defect.