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"major reorganization" is correct and usable in written English.
You can use it when you want to refer to a large-scale reorganization of a company, organization, or system. For example: "The company underwent a major reorganization this year, and saw improved results."
Exact(60)
Synapses, the connections between brain cells, are undergoing major reorganization.
My publishing house underwent a major reorganization, and my imprint was toast.
A multimillion-dollar deficit persists, and county officials are demanding a major reorganization.
GRADUAL CHANGE How can leaders avoid putting their companies through a major reorganization?
*The agency recently completed a major reorganization, which disrupted the work of many offices.
A major reorganization of the curricula and redesign of textbooks began in the years after 1989.
Mr. Rittereiser already initiated a major reorganization of the brokerage earlier this month.
The SANS results indicate that the major reorganization and homogenization occur at low strain.
Metamorphosis, although a period of major reorganization, is not so dramatic as that in frogs.
The announcement came after a major reorganization that G.M. announced on Tuesday.
As hostilities were waning (1435 49), Charles VII presided over a major reorganization of government.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com