Sentence examples for major regulatory component from inspiring English sources

One of the major regulatory component which responds to hypoxia to ensure cell survival and to promote angiogenesis is HIF-1α [ 2, 7].

Taken together, results from all the above statistical analyses suggested that the miRNAome is unlikely to be the major regulatory component responsible for the changed expression profiles of the protein-coding genes under cold stress.

Regulatory immune cells, mostly regulatory Foxp3+CD4+CD25+ T cells (Treg cells), have been identified as a major regulatory component of the adaptive immune response and are involved in H. pylori-related inflammation and bacterial persistence (Shen et al. 2010).

CYPD is a major regulatory component of the mPTP, and studies have found that its genetic ablation results in resistance to calcium-induced mPTP opening, a smaller myocardial infarct size, and resistance to the infarct-limiting effects of IPC.

In addition, ER stress caused increased polysome association of the mRNA encoding the major regulatory component for the rate-limiting step in GPI anchor biosynthesis, Dpm2, as well as the subsequent enzyme in the pathway, AfPIG-L.

The first of these, β-catenin is a major regulatory component of the VE-cadherin-β-catenin adhesive complex, and its level is tightly regulated by GSK-3β, followed by the phosphorylation-dependent ubiquitin-proteasome degradation pathway in a manner similar to the phosphorylation-dependent degradation of IκB [ 23].

For example, one of the major regulatory components of the PPACA legislation [ 12] was the establishment of the Patient-Centred OundereSubtitle D Institute (PCORI) under Subtitle D [ http://www.pcori.org/].

miRNAs have emerged as a major regulatory components of cell system, which are active in almost all of the multicellular organisms.

A comparison of the molecular mechanisms governing heart development in Drosophila and vertebrates reveals a remarkable conservation of all major regulatory components, including both signals and transcription factors (TFs) (Olson, 2006; Bodmer and Frasch, 2010).

PIK3R2 is a regulatory component of PI3K, a major member of the PI3K/Akt pathway, one of the top hubs in the MERGE-PW network (see Table 9).

The SCB motif is a binding site of the SBF protein, which is a complex of SWI4 (a DNA-binding component) and SWI6 (a regulatory component) [ 22], and SBF is a major regulator in the G1/S transition.