A second major chromatin regulating system is that of the Polycomb/trithorax groups (PcG/trxG) of genes.
A second major chromatin regulating system is that of the Polycomb/trithorax groups of genes which, respectively, maintain the repressed/activated state of euchromatin.
Recent findings suggest a mediating role of a major stress-regulating system, the hypothalamic-pituitary-adrenal (HPA) axis, in the association of stress with pain and pain hypersensitivity [ 3– 5].
This was conceived as a self-regulating system.
Tet operon is a tightly regulated system.
The renin-angiotensin system is a major endocrine/paracrine system that regulates blood pressure (BP) in our body [ 49], genes encoding components of this system have been strong candidates for the investigation of the genetic basis of essential hypertension and major targets for antihypertensive drugs [ 50].
The hypothalamic pituitary adrenal (HPA) axis, regulated by the corticotrophin-releasing factor (CRF), is the major centrally regulated neuroendocrine system responsible for rapid and strong responses to stress.
Mr. Wright noted that the last two major blackouts, in 1965 and 1977, occurred under highly regulated systems.
Announcing the award on Monday at the Karolinska Institute in Sweden, the Nobel Assembly's citation read that the award was "for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells".
James Rothman of Yale University; Randy Schekman of the University of California, Berkeley; and Thomas Südhof of Stanford University earned the award "for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells," according to the announcement from the Nobel Assembly at Karolinska Institute in Stockholm.
