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How this energy is released remains a major puzzle.
A major puzzle is why so few textbooks and medical schools deal with the phenomenon.
The way the electroweak scale and cosmological constant are connected remains to be a major puzzle.
I should add as an aside note that the fall in the unemployment rate remains a major puzzle.
Problems are quite challenging but ultimately solvable; the last major puzzle involving opening a Chinese safe is particularly ingenious.
Nathan said this enzyme presents a major puzzle, since it seems to work against the interests of the bacteria.
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Levin M. Regeneration: Recent advances, major puzzles, and biomedical opportunities.
All are simple questions, but in Argentina they can be major puzzles.
You have identified one of the major puzzles connected with radio galaxies and quasars.
"Terrell explores some major puzzles of human behavior in his searing first novel," Marilyn Stasio said here last year.
Across great swaths of nature... the major puzzles of existence have been pulled to pieces in the hands... of all-conquering and -consuming scientific rationality".
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