Sentence examples for major prognostic marker from inspiring English sources

For major prognostic marker studies, the two kinds of data cannot be extracted directly.

LOH at BRCA2 does not therefore appear to be a major prognostic marker in sporadic breast cancer.

The invasion of bladder cancer into the muscle layer of the bladder serves as major prognostic marker for the development of the treatment plan [ 3].

Estrogens control multiple functions in hormone-responsive breast cancer cells [ 2], and ERα, in particular, plays a major role in the etiology of the disease, serving as a major prognostic marker and therapeutic target in breast cancer management [ 2].

In addition, these data highlight the importance of DNA methylation analyses in revealing components of breast cancers, like the immune component described here, that were not that apparent on the basis of classical gene expression analyses (the latter having revealed principally the cell proliferation component as the major prognostic marker for breast cancer (Sotiriou & Pusztai, 2009)).

Here, a significant association was found between the existence of cryptococcosis-related radiological brain lesions at baseline and high serum or CSF antigen titers, two major prognostic markers [3].

In conclusion, our preliminary data of molecular markers do show a major potential role for MSI instability as prognostic marker, but await inclusion of more patients.

Moreover, miR-148b is considered as a major co-ordinator of malignancy or an independent prognostic marker since its expression is closely associated with tumour invasion and progression in both breast cancer and liver cancer [ 19, 23, 24].

To verify the prognostic potential of sFas in relation to the established prognostic marker IL-6 for sepsis development after major trauma, we established ROC curves for both parameters at each time point.

The CD4 lymphocyte count, currently regarded as the best prognostic marker for the development of AIDS, is a major criterion to decide on initiation of antiretroviral therapy.

BNP may therefore be an appropriate prognostic marker indicating the early development of postoperative severe sepsis after major surgery.