Sentence examples for major producing cells from inspiring English sources

Monocytes and macrophages from RA patients are targets of TNFα signals and the major producing cells of TNFα, which they present in significant amounts in membrane [ 27].

The assignment of the IFNβ producers to the group of Tip-DCs stands at first glance in contrast to a recent publication were splenic macrophages were shown to be the major IFNβ producing cells in listeriosis [9].

Figure  1C shows that CD19+ cells are the major WNT4 producing cells (~15 20-fold ~15 20-foldCD3+ cells express levels similandthatBMCD3+~0.86-fold).

It is well-known that STAT3 is critical in the differentiation of Th17 cells, the major IL-17 producing cells [ 14].

The IL-17 producing cells were major CD4 positive, but Foxp3 negative.

Immunofiuorescence results showed that IL-17 producing cells were major CD4 positive, but FOXP3 negative in ESCC tissues (Figure 1).

As the spleen turned out to be the major dwelling place of IFNβ producing cells after L. monocytogenes infection we focused our following in vivo experiments on the splenic IFNβ expressing cells.

Taking advantage of the direct cellular visualization of IFNβ production we were able to show that the spleen acts as the major dwelling place of IFNβ producing cells with a small subpopulation of cells (∼105 per spleen) being sufficient to provide this cytokine in biologically functional amounts.

The increase of the IFN-γ expression level and the CD4+ T-cell subpopulation in our results is closely correlated with a previous report that indicated that CD4+ T-cells were the major proliferating phenotype and IFN-γ producing cells [ 12].

HSCs are extensively studied due to its role as the major extracellular matrix producing cell upon hepatic injury, playing a key role in the progression of chronic liver diseases.

Although these studies were performed with PBMCs, it is probable that pDCs were the major source of IFNα given that they are the major IFNα-producing cells in peripheral blood.