Sentence examples for major process leading from inspiring English sources

However, despite the fact that the mechanisms influencing treatment responses are well known, it appears that the major process leading to chemotherapy resistance [4] is the ability of cancer cells to evade cell death signals.

This indicates that deletion is consistently more prevalent than substitution and is thus a major process leading to family inactivation.

Enhanced formation and accumulation of advanced glycation endproducts (AGEs), have been implicated as a major pathogenesis process leading to diabetic complications, normal aging, atherosclerosis, and Alzheimer's Disease.

Interspecies DNA transfer is a major biological process leading to the accumulation of mutations inherited by sexual reproduction among eukaryotes.

In particular, in the case of tumors in which prognosis is dependent on lymph node status and in which lymph node metastasis is a major biological process leading to distant tumor propagation, lymphangiogenesis inhibition is of utmost clinical importance.

In lead acid batteries, major aging processes, leading to gradual loss of performance, and eventually to the end of service life, are:.

Remarkably, the two major steps in this long process – leading to the ancestral fin anatomy of extant sarcopterygians and limb anatomy of extant tetrapods, respectively – occurred at the same nodes as the two major similarity bottlenecks that led to the striking derived myological similarity between the pectoral and pelvic appendages within each taxon.

The theory was first developed in 1978 by Nasa scientist Donald Kessler, who feared a major collision could accelerate this process, leading to the wiping out of most of our communications satellites and the creation of a debris belt that would make it impossible to send anything new, manned or unmanned into space for decades.

However, we see the way fatty acids interact with mitochondria in the cytosol of adipocytes as a major initiating event in the disease process leading to the metabolic syndrome and type 2 diabetes mellitus.

Byington focuses on two major aspects of state formation: as a social process leading to the formation of a state-level polity called Puyŏ, and as a political process associated with a variety of devices intended to assure the stability and perpetuation of the inegalitarian social structures of several early states in the Korea Manchuria region.

Several inhibitory compounds like acetate, hydroxymethylfurfural (HMF), and furfural are produced from the biomass pretreatment process leading to 'hydrolysate toxicity,' a major problem for microorganisms to achieve complete sugar utilization.