Sentence examples for major problem that from inspiring English sources

Resistance remains a major problem that limits the long-term responsiveness of the majority of the patients to these drugs.

"But this suggests a major problem that requires some attention".

One major problem that faced Johnson was the lack of support from other police forces.

If these allegations are true, the F.B.I. has a major problem that must be addressed immediately".

Corporate tax avoiders are a major problem that needs immediate action.

This, she says, "is a major problem that has to be addressed".

"We are facing a major problem that could get worse quickly," he said.

Our country's debt is a major problem that is slowing economic growth and inhibiting job creation.

A. This is a a huge issue, a major problem that has a profound and deleterious impact on the district.

French finance minister Pierre Moscovici said: "I don't see a major problem that could be an obstacle.

Mr. Rajoy, who took office in December, quickly identified the regional government spending as a major problem that has to be dealt with.