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As this knowledge is missing, one major problem in this context is to define adequate features to train the classifiers for each structural element.
Specifically, the major problem in this context, and the main topic of this paper, relates to the inference of causal interactions among genes from observational data.
A major problem in this context, however, is that even larger sample sizes are required to detect non-additive alleles in GWA studies.
A major problem in this context seems to be that a lower rate of cancer-related deaths after combined treatment is counterbalanced by a higher rate of treatment-associated mortality.
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Dyskinesia was not a major problem in this study.
The problem of child sexual abuse is a major problem in this country and elsewhere too.
Water pollution is a major problem in the global context.
Surface and ground water contamination caused by anthropogenic pollutants has been recorded as a major problem in the global context (Satya et al. 2011).
There are two major problems in this approach.
Student authentication was not seen as a major problem in any of the contexts, as this was felt to be well controlled through face-to-face proctored assessments, though the problem of assuring effective authentication was seen by many teachers as a barrier to increased use of e-assessment.
"Half a World From the Gulf, a Spill Scourge 5 Decades Old" (front page, June 17), reporting that spills are a major problem in the Niger Delta, misses crucial context that explains why they happen.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com