Sentence examples for major problem given from inspiring English sources

In some other state, that might be a major problem given the mood of voters this election season.

The foundations of these high-rise buildings posed a major problem, given the soft clay soil of central Chicago.

He said that the Roma did not present a major problem, given their small numbers, and that the expulsion campaign had been going on for a few years.

The providers who stayed in the program often had contractors who were good at the technical aspects of their jobs but were not at record keeping, Mr. Irvine said — a major problem given federal audit procedures and other requirements.

Excess demand was not mentioned as a major problem, given that more demand generates greater income based on productivity.

In particular, the management of platinum-resistant disease poses a major problem given the limited effectiveness of nonplatinum compounds in this setting.

The Colts' run defense, however, was a major problem, giving up 2,768 yards on the ground, an average of 173 per game and last in the NFL.

In most cases, improper priors can be used in Bayesian analysis without major problems given that a proper posterior distribution can be obtained [ 27].

It has been observed that there are two major problems giving rise to performance degradation of the system in terms of number of users and type of code.

Today, inappropriate prescribing for the elderly is considered a major public health problem, given its association with morbidity and mortality and in view of health service costs resulting from adverse reactions [ 10, 11].

This widespread use of a single class of insecticide could result in development of more insecticide resistance in the mosquito vectors and lead to a major public health problem given the limited availability of alternative insecticides [ 9].