Sentence examples for major practical difficulty from inspiring English sources

A major practical difficulty is accurately positioning the TMS coil within the MRI scanner for stimulating a particular area of brain cortex.

The lack of consensus on criteria for assessment of results is often ranked as a major practical difficulty of this kind of research.

However, a major practical difficulty associated with this approach is the large and erratic variability of quantile estimates with respect to the threshold value, which is not known a priori.

Development teams perceived this feature of delivery as posing major practical and conceptual difficulties, thereby challenging its feasibility in an NHS context.

Many investigators have stated that the practical difficulty of returning incidental findings is a major barrier to reporting back incidental findings to participants.

Aside from the EU membership difficulty, even before its settling the dispute has caused no major practical problems.

Their decisions will have major practical implications.

That is not without practical difficulty, of course.

This causes major practical problems for families.

The practical difficulty of securing such investments will be equally familiar.

The Electoral Commission sees no practical difficulty in enabling prisoners to vote.