Your English writing platform
Discover LudwigSuggestions(1)
Exact(1)
The story of discovery of the major platelet syntaxin followed a similar course to that of the VAMPs.
Similar(59)
c) Platelet glycoprotein Ib/IX/V complex (GPIb/IX/V complex) is the major platelet receptor for von Willebrand factor.
αIIb exclusively associates with β3 to form the major platelet integrin αIIbβ3 (gpIIb/IIIa or CD41/CD61).
SFKs are essential for initiating and propagating signaling from several major platelet tyrosine kinase-linked receptors.
(2) CD148 plays a critical role in signaling through GPVI and the major platelet integrin, αIIbβ3.
Platelet activation by thrombin induces increased cell-surface expression of the major platelet integrin αIIbβ3, which binds and assembles FN via a fibrin-independent mechanism [ 38- 44].
Platelet endothelial cell adhesion molecule-1 (PECAM-1) inhibits platelet response to collagen and may also inhibit two other major platelet agonists ADP and thrombin although this has been less well explored.
However, all major plasma membrane syntaxins, syntaxin 1 3, are cleaved by BoNT/C and the only known resistant paralog, syntaxin 4 [43], is expressed only at low levels and in specific synapses [44].
The major function of syntaxins appears to be their direct involvement in transpairing between synaptobrevin and syntaxin, which physically forces the synaptic vesicle membrane and the presynaptic membrane into contact, a final step of synaptic vesicle exocytosis.
A little background: Human blood is made up of a few major components, platelets and plasma being two of them.
Two major syntaxin-1-containing complexes, migrating at ∼100 kDa and ∼80 kDa, were detected (Fig. S2A).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com