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The phrase "major pillar of" is correct and usable in written English.
You can use it to refer to something that is a fundamental part, base, or support of a larger entity. For example, you might say, "The major pillars of the organization are its values, its mission statement, and its customer service."
Exact(38)
They are a major pillar of the British government's electricity market reform.
But for hours, the fate of the bill — and by extension, a major pillar of Mr. Corzine's agenda — was uncertain.
Volkswagen said football was a major pillar of its sponsoring strategy that it would continue to pursue in the future.
A major pillar of my own research is to reconstruct forest fire frequency and spatial patterns using fire-scar dendrochronology.
If the current growth rate continues, medical biotechnology will soon become a major pillar of health science.
Mr. Obama's new initiative could be a major pillar of a strategy that is based on generosity, good science and rigorous management.
Similar(22)
We're moving forward with four major pillars of activity.
In the past, they were one of the major pillars of the global economy".
"These are traditional major pillars of the U.S. economy, as opposed to upstarts or professional services or finance firms with a highly fluid work force".
In a speech at a conference in Beijing this summer, Shing-Tung Yau of Harvard said the understanding of three-dimensional space brought about by Poincaré's conjecture could be one of the major pillars of math in the 21st century.
Since its discovery in 1964, ancient light called the Cosmic Microwave Background (CMB), has revealed a wealth of information about the early Universe, and is one of the major pillars of evidence for the Big Bang.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com