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This study identified major physiological systems that participate in the PAH-induced stress response in Arabidopsis.
This integrated systems microarray represents four major physiological systems with 9,833 unique cDNA clones from the metabolic and somatic systems and 7,937 unique cDNA clones from the neuroendocrine and reproductive systems [ 27].
It is easy to speculate that modulation of the phosphorylation status of MEF2 in adult Drosophila may ameliorate the affects of aging on two major physiological systems, with profound consequences for the aging organism.
The study was designed and aimed to evaluate whether exposure of HBA is safe and not altering the activities of major physiological systems in comparison to BA, with the intention that the results would provide information on the safety of the compound.
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Two major physiological anticoagulant systems, the activated protein C (APC -thrombomodulin (TM) system APC -thrombomodulinn (ATM-heparan systemte system, hand been exthesively studied antithrombintAT -heparan
The PC pathway is both a major physiological anticoagulant system and a central link between inflammation and coagulation.
The major physiological function of plasminogen system (PAI-1, tPA, plasminogen, and others) is to regulate physiological fibrinolysis.
Under normal conditions, the sex difference in kidney V2R expression does not appear to cause major physiological differences, but if the system is stressed, differences in osmoregulation occur that can affect the brain.
The major physiological response to stress involves activations of neuroendocrine systems, mainly through the hypothalamus-pituitary-adrenal (HPA) axis.
In addition, hepatic GSH represents the major systemic store which can be mobilised as required to supply other physiological systems [25].
For example, older patients who suffer severe disability secondary to a major accident or stroke may maintain relatively intact function in other physiological systems, and thus are not frail.
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