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For instance, in glucose minimal media, biofilm lifestyle cycle of P. aeruginosa PAO1 can be subdivided into five major phenotypic steps.
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Because AOX expression at any stage of the fly life-cycle had no effect on the major phenotypic features of tko 25t mutants, we considered the hypothesis that the steps in mitochondrial electron flow that AOX bypasses may not be crucial determinants of the phenotype.
One of the early steps in the invasion-metastasis cascade includes epithelial mesenchymal transition (EMT) through which polarized epithelial cells undergo major phenotypic changes and acquire a more mesenchymal morphology.
The LOD score is highly significant (P < 0.0001) indicating a major phenotypic effect of Bsdr1.
The gene-disruption mutants segregated from NG6441 and the WT were grown under controlled conditions to assess major phenotypic differences.
The transgenic line exhibited no major phenotypic alterations.
The major phenotypic differentiator between L. lactis ssp.
Reverse genetic studies are needed to determine if any of these substitutions cause major phenotypic changes.
These correlations may account for some of the major phenotypic features reported in VCFS.
Overexpression or MO knockdown alone did not cause major phenotypic abnormalities or developmental delay.
Factors that influence the susceptibility to, and progression of, these major phenotypic forms are currently unknown.
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