Sentence examples for major phenotypic shift from inspiring English sources

It has been suggested that a major phenotypic shift occurs in OA toward a de-differentiated chondrocyte [ 40].

Since that time domesticated cattle have experienced various selective pressures that have resulted in major phenotypic shifts for a range of traits.

A fourth factor could be that artificial selection for meat and dairy traits has mainly evolved through polygenic adaptation, shifting the allele frequencies of hundreds or thousands of loci instead of fixing novel mutations with major phenotypic effects.

Differentiation potential is also a major phenotypic variable among hMSCs.

Hale, T. M. Persistent phenotypic shift in cardiac fibroblasts: impact of transient renin angiotensin system inhibition.

The hallmarks of cancer outline the major phenotypic changes underlying the oncogenic process1,2.

In addition, we examined the possibility that endogenous miR-1246 levels are elevated in mutp53-reprogrammed macrophages, driving their phenotypic shift.

The discovery that the mutation itself is a transposable element will stimulate further debate about the importance of 'jumping genes' as a source of major phenotypic novelty3.